http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Article/list/47453 For pharmacists, from <em>Drug Topics</em>: News and features for pharmacists about clinical trials, newly approved drugs, and new practices in clinical pharmacy 2010-07-30T03:58:59Z http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/CMS-favors-continued-local-pharmacy-distribution-o/ArticleStandard/Article/detail/679708?contextCategoryId=47453&ref=25 The Centers for Medicare &amp;amp; Medicaid Services (CMS) issued a proposed regulation on June 25 that would exempt community pharmacies from the upcoming bidding process for Medicare Part B diabetes-testing supplies, along with instructions that exempt most independent community pharmacies from accreditation requirements. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679708null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Coumadin-1-mg-tablet-blister-packs-recalled/ArticleStandard/Article/detail/679704?contextCategoryId=47453&ref=25 A recall of 3 lots of physician sample blister packs of Coumadin 1-mg tablets and 5 lots of Coumadin 1-mg tablet hospital unit dose blister packs has been initiated by Bristol-Myers Squibb. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679704null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Updated-recommendations-for-endometriosis-released/ArticleStandard/Article/detail/679707?contextCategoryId=47453&ref=25 Women who suffer from endometriosis-related pain should be treated first with conservative, nonsurgical approaches and then with more invasive options if pain does not resolve, and with hysterectomy only as a last resort, according to a practice bulletin issued by the American College of Obstetricians and Gynecologists and published in the July issue of Obstetrics &amp;amp; Gynecology, reported HealthDay News. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679707null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Cardiology-clinicians-neglect-to-determine-patient/ArticleStandard/Article/detail/679702?contextCategoryId=47453&ref=25 The use of nutraceuticals and nonprescription over-the-counter (OTC) drugs may be high; however, the use of these agents may largely be ignored by cardiovascular clinicians, according to research published in the July 6 issue of the Annals of Internal Medicine. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679702null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Recent-low-back-pain-guidelines-offer-similar-advi/ArticleStandard/Article/detail/679742?contextCategoryId=47453&ref=25 Recent clinical practice guidelines offer similar recommendations for assessing and managing low back pain, and clinicians can improve patient care by adopting these recommendations, according to a review published in the June issue of The Spine Journal, reported HealthDay News. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679742null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Statin-use-lowers-after-gastric-bypass-surgery/ArticleStandard/Article/detail/679706?contextCategoryId=47453&ref=25 Long-term data from a retrospective cohort study showed that hyperlipidemic obese patients had more than a 90% reduction in their need of lipid-lowering therapy following laparoscopic gastric-bypass surgery, MedPage Today reported. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679706null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Fluzone-High-Dose-vaccine-covered-under-Medicare-P/ArticleStandard/Article/detail/679710?contextCategoryId=47453&ref=25 Written confirmation is now available from the Centers for Medicare and Medicaid Services indicating that Fluzone High-Dose (Sanofi Pasteur) influenza virus vaccine for patients 65 years or older is a benefit covered by Medicare Part B and will be reimbursed for the upcoming 2010?11 influenza season. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679710null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/DEA-seeks-comments-on-dispensing-controlled-drugs-/ArticleStandard/Article/detail/679705?contextCategoryId=47453&ref=25 The Drug Enforcement Administration (DEA) has issued a notice in the Federal Register requesting input about the dispensing of controlled substances for residents in long-term-care (LTC) facilities. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679705null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Folic-acid-vitamin-Bsub12sub-do-not-reduce-vascula/ArticleStandard/Article/detail/679700?contextCategoryId=47453&ref=25 Supplementation with folic acid and vitamin B12 over an extended period does not have a beneficial effect on vascular outcomes in individuals who have had a myocardial infarction, but it also poses no excess cancer risk, according to a study in the June 23/30 issue of the Journal of the American Medical Association, HealthDay News reported. 2010-07-20T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/302010/679700null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Low-dose-HRT-patches-carry-26-less-risk-than-oral-/ArticleStandard/Article/detail/678168?contextCategoryId=47453&ref=25 Hormone replacement therapy (HRT) skin patches containing low doses of estrogen carry less risk of stroke than oral therapy and may represent a safer alternative. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678168null XML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Diabetes-prevention-Meta-analysis-finds-glitazones/ArticleStandard/Article/detail/676954?contextCategoryId=47453&ref=25 A systematic review assessing the comparative effectiveness of oral anti-diabetic drugs for preventing patients at high risk from progressing to type 2 diabetes has found glitazones (pioglitazone, rosiglitazone), biguanides (metformin), and alpha-glucosidase inhibitors (AGIs; acarbose, voglibose) reduced the relative risk of diabetes by as much as 63%, whereas insulin secretagogues (sulfonylureas and glinides) had no effect. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676954null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Study-validates-switch-to-generic-anticonvulsants/ArticleStandard/Article/detail/678166?contextCategoryId=47453&ref=25 Switching from branded to generic drugs for epilepsy did not cause increased incidents or utilization changes among patients, according to new study results. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678166null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Dietary-supplements-Beware-of-fake-remedies/ArticleStandard/Article/detail/678207?contextCategoryId=47453&ref=25 The Dietary Supplement Health and Education Act of 1994 greatly reduced FDA involvement in assessing the safety of dietary supplements, leaving pharmacists with the problem of obtaining accurate information with which to advise patients. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678207null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Feature+Articles/Inhaled-insulin-appears-to-be-on-the-rebound/ArticleStandard/Article/detail/678163?contextCategoryId=47453&ref=25 Inhaled insulin may be making a comeback. That's the hope at MannKind, a California-based biopharmaceutical company developing a rapid-acting inhaled insulin known as Afrezza (insulin human rDNA origin). 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678163/inhaled_insulin_195x210_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Vitamins-and-dietary-supplements-Why-pharmacists-r/ArticleStandard/Article/detail/678152?contextCategoryId=47453&ref=25 As Americans increasingly turn to vitamins and herbal supplements as alternatives to prescription drug use, medical professionals and government leaders worry that few realize the implications. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678152/JULY201010_cv1_RFC_195x210_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Long-Term+Care/Controlled-substances-LTC-nurses-and-verbal-drug-o/ArticleStandard/Article/detail/678155?contextCategoryId=47453&ref=25 The relationship between prescribing practitioners and nurses working in a long-term-care (LTC) facility is of significant concern to the LTC facility when controlled substances are needed. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678155null XML http://drugtopics.modernmedicine.com/drugtopics/Associations/DEA-issues-interim-final-rule-on-e-prescribing-of-/ArticleStandard/Article/detail/678161?contextCategoryId=47453&ref=25 The Drug Enforcement Administration has released its long-awaited interim final rule for electronic prescribing of controlled substances. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678161null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/FDA-approves-first-device-for-severe-persistent-as/ArticleStandard/Article/detail/678159?contextCategoryId=47453&ref=25 The first non-drug treatment for severe asthma that is not well controlled by anti-inflammatory medicines won FDA approval April 27. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678159null XML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-announces-ongoing-cardiovascular-safety-review/ArticleStandard/Article/detail/676741?contextCategoryId=47453&ref=25 FDA has announced that the agency is currently evaluating whether the use of the angiotensin II receptor blocker (ARB) olmesartan (Benicar, Daiichi Sankyo; also sold in combination with hydrocholorothiazide as Benicar HCT) was associated with increased cardiovascular mortality. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676741null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/ASHP-guidelines-foster-remote-pharmacy-management/ArticleStandard/Article/detail/678154?contextCategoryId=47453&ref=25 Pharmacy directors who want to &amp;mdash; or have to &amp;mdash; operate 24/7 but don't have the staff to cover all 3 shifts have a new ally, the American Society of Health-System Pharmacists (ASHP). 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/282010/678154/ASHP_RMOP_195x210_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Chains+%26+Business/MTM-bill-seeks-to-help-seniors-manage-medications-/ArticleStandard/Article/detail/676930?contextCategoryId=47453&ref=25 Sens. Kay R. Hagan (D-N.C.) and Al Franken (D-Minn.) have introduced The Medication Therapy Management (MTM) Expanded Benefits Act, a bill that will allow seniors with one chronic illness to thoroughly review all their medications with a pharmacist in a one-on-one session. 2010-07-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676930null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Diabetic-retinopathy-reduced-by-intensive/ArticleStandard/Article/detail/677224?contextCategoryId=47453&ref=25 Five-year data from a seminal study in patients with type 2 diabetes who are at especially high risk of heart disease show that intensive glucose control does slow the progression of microvascular disease, but mortality is increased and there is no benefit on macrovascular complications. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677224null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Glycemic-control-better-with-a-sensor-aug/ArticleStandard/Article/detail/677100?contextCategoryId=47453&ref=25 Use of a sensor-augmented pump is superior to multiple daily insulin injections in reducing glycated hemoglobin levels without an increased risk of hypoglycemia in both adults and children with type 1 diabetes who are not in good control on multiple daily injections, said Richard M Bergenstal, MD. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677100null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Blood-pressure-target-for-high-risk-type-/ArticleStandard/Article/detail/677253?contextCategoryId=47453&ref=25 At 5 years? follow-up, intensive blood-pressure reduction to a target systolic blood pressure (SBP) less than 120 mm Hg did not reduce the risk of a composite cardiovascular outcome, compared with a target SBP of less than 140 mm Hg in patients with type 2 diabetes at high risk of cardiovascular events, although it did reduce the incidence of stroke, said William Cushman, MD, who presented the results from the blood pressure portion of the ACCORD (Action to Control Cardiovascular Risk in Diabetes) study to a gathering at the 70th Scientific Sessions of the American Diabetes Association in Orlando, Fla. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677253null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-The-latest-in-nonnutritive-sweeteners/ArticleStandard/Article/detail/677143?contextCategoryId=47453&ref=25 Patients and providers who look for saccharine packets may like the product&amp;mdash;or they may not realize the range of nonnutritive, noncaloric sweeteners currently available. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677143null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Community-based-lifestyle-program-helps-o/ArticleStandard/Article/detail/677102?contextCategoryId=47453&ref=25 A community-based behavioral lifestyle intervention results in significant reductions in glycated hemoglobin, fasting blood glucose, and body weight in overweight/obese individuals with prediabetes, said David Goff Jr, MD, PHD. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677102null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Findings-add-fuel-to-the-rosiglitazone-co/ArticleStandard/Article/detail/677220?contextCategoryId=47453&ref=25 A new post-hoc study of rosiglitazone and cardiac events in patients with type 2 diabetes is adding to the controversy surrounding the thiazolidinedione (TZD) agent. Lead author Richard Bach, MD, associate professor of medicine, Washington University, St. Louis, Mo., presented the new data during a late-breaking clinical study symposium Tuesday morning at the 70th Scientific Sessions of the American Diabetes Association, taking place in Orlando, Fla. 2010-07-01T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/677220null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Will-DPP-4-inhibitors-replace-sulfonylure/ArticleStandard/Article/detail/676941?contextCategoryId=47453&ref=25 Although their ability to control glycemia is essentially the same, do other merits of dipeptidyl peptidase 4 (DPP-4) inhibitors favor their replacing sulfonylureas in the treatment armamentarium for type 2 diabetes? Michael Nauck, MD, and David Matthews, FRCP, were on opposing sides of this issue. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676941null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Metformin-associated-with-lower-risk-of-m/ArticleStandard/Article/detail/676948?contextCategoryId=47453&ref=25 In patients with diabetes and concomitant heart failure who are naive to oral antidiabetic drugs, the introduction of metformin use is associated with a lower risk of mortality than the introduction of other oral antidiabetic drugs, found Dean T Eurich, PhD. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676948null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Among-older-diabetics-improvements-in-HbAsub1csub-/ArticleStandard/Article/detail/676996?contextCategoryId=47453&ref=25 A telemedicine intervention in older adults with diabetes improved hemoglobin (Hb) A1c levels, and this improvement in HbA1c was associated with more frequent uploading of glucose values, found Ruth Weinstock, MD, PhD, addressing a gathering at the 70th Scientific Sessions of the American Diabetes Association meeting in Orlando, Florida. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676996null HTML http://drugtopics.modernmedicine.com/drugtopics/Top+News/ADA-2010-Gut-bacteria-can-affect-obesity/ArticleStandard/Article/detail/676995?contextCategoryId=47453&ref=25 Obesity and leanness are more than calories in and energy out. The amount of adipose tissue an individual carries is also a function of his or her intestinal microbiota. Research in mice and humans suggests that individuals with more Firmicutes and fewer Bacteroidetes tend to be more obese. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676995null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Hypoglycemic-episodes-linked-to-oral-anti/ArticleStandard/Article/detail/676949?contextCategoryId=47453&ref=25 Hypoglycemic episodes in type 2 diabetes predict discontinuation of oral antidiabetic drugs as well as higher costs of care. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676949null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Herbals-helpful-for-diabetes-care-but-the/ArticleStandard/Article/detail/676999?contextCategoryId=47453&ref=25 Herbals and supplements such as silymarin (milk thistle), fish oil, and red rice yeast can improve some of the conditions associated with diabetes, but the evidence is slim. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676999null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Cardiac-disease-in-diabetes-still-a-black/ArticleStandard/Article/detail/676997?contextCategoryId=47453&ref=25 In 1992, researcher Edwin Bierman, MD, described the development of cardiovascular disease in diabetes as a black box. Nearly 20 years later, it is still a black box. 2010-06-30T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676997null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Diet-can-affect-type-2-diabetes-risk/ArticleStandard/Article/detail/676730?contextCategoryId=47453&ref=25 Dietary choices can have a discernable effect on the risk of developing type 2 diabetes. That conclusion is based on analysis of men in the Health Professionals Follow-Up Study (HPFS), which followed 41,212 men for up to 20 years. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676730null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-One-year-data-on-exenatide-show-that-impr/ArticleStandard/Article/detail/676732?contextCategoryId=47453&ref=25 In patients with type 2 diabetes, treatment with exenatide once weekly for 1 year results in sustained improvements in glycemic control, body weight, cardiovascular risk markers, and markers of hepatic injury, according to a pooled analysis of 2 large clinical trials. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676732null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Cell-phone-reporting-coaching-can-improve/ArticleStandard/Article/detail/676740?contextCategoryId=47453&ref=25 Clinical reporting and coaching systems can significantly reduce glycated hemoglobin levels without increasing the costs of care. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676740null HTML http://drugtopics.modernmedicine.com/drugtopics/Treatment+Areas%3A+Diabetes/ADA-2010-Blame-calories-not-fructose/ArticleStandard/Article/detail/676735?contextCategoryId=47453&ref=25 Fructose is the sugar consumers love to hate. It gets the blame for obesity, metabolic syndrome, and a variety of dietary ills. But according to at least one expert, the fructose content in high-fructose corn syrup just isn't that high. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676735null HTML http://drugtopics.modernmedicine.com/drugtopics/Top+News/ADA-2010-Glycated-hemoglobin-levels-correlate-stro/ArticleStandard/Article/detail/676728?contextCategoryId=47453&ref=25 An ancillary study to the ARIC (Atherosclerosis Risk in Communities) study supports the most recent (2010) ADA risk categories of glycated hemoglobin in identifying future risk of developing diabetes and macrovascular and microvascular disease. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676728null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Liraglutide-clinical-trial-program-sugges/ArticleStandard/Article/detail/676737?contextCategoryId=47453&ref=25 A post hoc analysis of 5 clinical trials of liraglutide suggests that it was significantly better than active comparators on a composite end point of glycated hemoglobin less than 7% without hypoglycemia or weight gain, reported French investigators. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676737null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Bolster-self-determination-to-boost-exerc/ArticleStandard/Article/detail/676739?contextCategoryId=47453&ref=25 Exercise research has found that boosting patients' self-determination is an effective way to improve their motivation to exercise. 2010-06-29T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676739null HTML http://drugtopics.modernmedicine.com/drugtopics/Top+News/ADA-2010-Liraglutide-more-successful-than-sitaglip/ArticleStandard/Article/detail/676389?contextCategoryId=47453&ref=25 Liraglutide is more successful in reducing glycated hemoglobin levels to 7% or less regardless of baseline glycated hemoglobin level compared with sitagliptin in adults with type 2 diabetes, said Melanie Davies, MD, MB ChB, professor of diabetes medicine, University of Leicester, United Kingdom. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676389null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-TZDs-associated-with-increased-hip-fractu/ArticleStandard/Article/detail/676434?contextCategoryId=47453&ref=25 New data from Scotland suggest that drug regulators should change labeling on thiazolidinediones to warn of elevated risk for hip fractures in both men and women. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676434null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Is-HDL-too-much-of-a-good-thing-in-type-1/ArticleStandard/Article/detail/676397?contextCategoryId=47453&ref=25 Too much high-density lipoprotein (HDL) cholesterol could be harmful for women with type 1 diabetes. Men with type 1 diabetes, however, continue to experience cardioprotection with increasing HDL, said Tina Costacou, PhD. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676397null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Obesity-poor-glycemic-control-predict-whi/ArticleStandard/Article/detail/676447?contextCategoryId=47453&ref=25 In clinical practice, exenatide is often started in patients with type 2 diabetes who are on insulin therapy, even though the prescribing information states that the concurrent use of exenatide with insulin has not been studied and cannot be recommended, according to analysis of a large nationwide database. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676447null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Exenatide-beats-insulin-glargine-in-glyca/ArticleStandard/Article/detail/676393?contextCategoryId=47453&ref=25 Patients who are not well controlled on metformin may get better control of glycated hemoglobin levels and weight using once-weekly exenatide than by titrating insulin glargine. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676393null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Diabetes-an-independent-risk-factor-for-v/ArticleStandard/Article/detail/676429?contextCategoryId=47453&ref=25 New data suggest that although diabetes doubles the risk of vascular disease, elevated fasting glucose has little effect on the risk of coronary heart disease or major ischemic events. 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676429null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/ADA-2010-Near-agreement-on-CV-risk-assessment-for-/ArticleStandard/Article/detail/676432?contextCategoryId=47453&ref=25 It was billed as a debate, but played as a mild disagreement. Should new diabetes drugs submitted to the FDA have a higher bar for cardiovascular safety than other drugs? 2010-06-28T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/272010/676432null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/International-Public-Health-amp-Pharmacy-Issues-Co/ArticleStandard/Article/detail/675614?contextCategoryId=47453&ref=25 Pharmacists Planning Service, Inc. is calling for papers for its 17th International Public Health &amp;amp; Pharmacy Issues Conference aboard Royal Caribbean's Adventure of the Seas. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675614null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Community-pharmacists-to-gather-for-annual-NCPA-co/ArticleStandard/Article/detail/675611?contextCategoryId=47453&ref=25 The National Community Pharmacists Association (NCPA) will present the latest in pharmacy education, case studies, and real-world, business-oriented information for the independent community-pharmacy industry at its 112th Annual Convention and Trade Exposition taking place at the Pennsylvania Convention Center in Philadelphia Oct. 23 to 27. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675611null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Counterfeit-Tamiflu-sold-on-Internet-puts-consumer/ArticleStandard/Article/detail/675595?contextCategoryId=47453&ref=25 FDA notified consumers and healthcare professionals that a product represented as &#34;Generic Tamiflu&#34; being sold on the Internet does not contain Tamiflu's active ingredient, oseltamivir, but cloxacillin, an ingredient in the same class of antibiotics as penicillin. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675595null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-probes-hundreds-of-complaints-about-Johnson-am/ArticleStandard/Article/detail/675620?contextCategoryId=47453&ref=25 FDA is investigating hundreds of consumer complaints involving children's medicines recalled by Johnson &amp;amp; Johnson on April 30, according to a congressional memo, the Associated Press reported. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675620null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-to-post-risk-summaries-of-approved-drugs-on-ne/ArticleStandard/Article/detail/675591?contextCategoryId=47453&ref=25 FDA announced that it will release risk summaries about medicines approved after September 2007 and post them quarterly to a publicly accessible website, Reuters reported. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675591null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-OKs-2009-H1N1-influenza-test-for-use-beyond-em/ArticleStandard/Article/detail/675479?contextCategoryId=47453&ref=25 FDA has cleared Simplexa Influenza A H1N1 (2009), a test for the 2009 H1N1 influenza virus in patients with signs and symptoms of respiratory infection. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675479null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-sends-letters-to-Illumina-and-genomics-suspect/ArticleStandard/Article/detail/675491?contextCategoryId=47453&ref=25 FDA has informed four consumer genomics services providers and Illumina that it believes the firms are selling unapproved diagnostic devices, according to a report published by the GenomeWeb Daily News. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675491null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Overuse-of-antibiotics-spurs-vicious-cycle/ArticleStandard/Article/detail/675613?contextCategoryId=47453&ref=25 Patients whose doctors over-prescribe antibiotics may develop drug resistance that can last up to a year, putting them and others at risk when more serious treatment is needed, according to a study published in May in the British Medical Journal. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675613null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Childrens-consumption-of-chronic-medications-on-th/ArticleStandard/Article/detail/675456?contextCategoryId=47453&ref=25 In 2009, the drug trend for children, a measure of prescription-spending growth, increased 10.8%, driven by a 5% increase in drug utilization and higher medication costs, according to the Medco &#34;2010 Drug Trend Report.&#34; 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675456null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/CVS-Caremark-Generation-Health-outline-target-medi/ArticleStandard/Article/detail/675487?contextCategoryId=47453&ref=25 CVS Caremark and Generation Health announced 13 drug therapies that will be included in the initial offering of their integrated Genetic Benefit Management service. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675487null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/Metformin-linked-to-vitamin-deficiency/ArticleStandard/Article/detail/675622?contextCategoryId=47453&ref=25 Patients treated over long periods with the diabetes drug metformin (Glucophage, Bristol-Myers Squibb) are at risk of developing vitamin-B12 deficiency, according to a study published in the British Medical Journal, Reuters has reported. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675622null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/FDA-debuts-new-educational-video-series-on-drug-sa/ArticleStandard/Article/detail/675593?contextCategoryId=47453&ref=25 FDA last month launched &#34;FDA Drug Info Rounds,&#34; a new educational video series for pharmacists. 2010-06-23T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/262010/675593null HTML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/2009-Top-200-branded-drugs-by-total-prescriptions/ArticleStandard/Article/detail/674969?contextCategoryId=47453&ref=25 Which drugs were most popular in 2009? Check out Drug Topics' list of the Top 200 branded drugs in 2009, ranked by total prescriptions. 2010-06-17T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/252010/674969null PDF http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/2009-Top-200-branded-drugs-by-retail-dollars/ArticleStandard/Article/detail/674961?contextCategoryId=47453&ref=25 Which drugs were most popular in 2009? Check out Drug Topics' list of the Top 200 branded drugs in 2009, ranked by retail dollars. 2010-06-17T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/252010/674961null PDF http://drugtopics.modernmedicine.com/drugtopics/Chains+%26+Business/2009-Top-200-generic-drugs-by-retail-dollars/ArticleStandard/Article/detail/674976?contextCategoryId=47453&ref=25 Which drugs were most popular in 2009? Check out Drug Topics' lists of the Top 200 generic drugs in 2009, ranked by retail dollars. 2010-06-17T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/252010/674976null PDF http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/2009-Top-200-generic-drugs-by-total-prescriptions/ArticleStandard/Article/detail/674982?contextCategoryId=47453&ref=25 Which drugs were most popular in 2009? Check out Drug Topics' list of the Top 200 generic drugs in 2009, ranked by total prescriptions. 2010-06-17T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/252010/674982null PDF http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Aggressive-lipid-control-fails-to-benefit-type-2-d/ArticleStandard/Article/detail/673892?contextCategoryId=47453&ref=25 Adding fenofibrate to statin therapy fails to reduce cardiovascular events in patients with type 2 diabetes, according to results of the first trial to evaluate combination therapy presented at the 59th annual scientific session of the American College of Cardiology. 2010-06-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/242010/673892/June2010_bp_hba1c_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Personalized-medicine-and-the-future-of-pharmacy/ArticleStandard/Article/detail/673894?contextCategoryId=47453&ref=25 The promise of personalized medicine is approaching realization. As more medications are developed, pharmacists will be on the front line of individualized prescribing based upon genome-based diagnostic tests. 2010-06-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/242010/673894/June2010cvr-195X210_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Over+the+Counter/Obesity-screening-and-diet-counseling-A-business-v/CME/Article/detail/669782?contextCategoryId=47453&ref=25 In light of the fact that significant morbidity and mortality are associated with overweight and obesity, it is important to screen, assess, and manage these individuals early and intensively. 2010-05-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/cme/drugtopics/202010/669782null REMOTE http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/New-acetaminophen-labeling-rule-takes-effect/ArticleStandard/Article/detail/670440?contextCategoryId=47453&ref=25 New OTC packaging intended to enhance patient safety began appearing on pharmacy shelves after a new rule for OTC internal analgesic, antipyretic, and antirheumatic drug products took effect on April 29, 2010. 2010-05-14T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/212010/670440null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/FDA-recommends-new-dosing-for-colchicine-when-co-a/ArticleStandard/Article/detail/670436?contextCategoryId=47453&ref=25 The FDA issued new label information on May 6 affecting all approved protease inhibitors for treatment of HIV when co-administered with colchicine (Colcrys, USP). 2010-05-14T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/212010/670436null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Study-finds-many-patients-with-chronic-illnesses-n/ArticleStandard/Article/detail/670438?contextCategoryId=47453&ref=25 A significant number of patients with chronic illnesses are not filling their prescriptions, according to a new study conducted by CVS Caremark and Horizon Blue Cross Blue Shield of New Jersey. 2010-05-14T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/212010/670438null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Study-results-confirm-safety-of-shingles-vaccine-i/ArticleStandard/Article/detail/670442?contextCategoryId=47453&ref=25 In a large randomized, double-blind, placebo-controlled study that evaluated the general safety of the live herpes zoster vaccine (Zostavax, Merck) in adults aged 60 or older, the safety profile of ZOSTAVAX was similar to that of placebo with respect to serious adverse events. 2010-05-14T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/212010/670442null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/FDA-approves-new-treatment-option-for-advanced-pro/ArticleStandard/Article/detail/670434?contextCategoryId=47453&ref=25 The FDA on April 29 announced the approval of sipuleucel-T (Provenge, Dendreon Corp.) for the treatment of certain men with prostate cancer, marking the first approval of a vaccine to treat cancer. 2010-05-14T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/212010/670434null HTML http://drugtopics.modernmedicine.com/drugtopics/Associations/Koda-Kimble-wins-Remington/ArticleStandard/Article/detail/668534?contextCategoryId=47453&ref=25 Clinical pharmacy pioneer Mary Anne Koda-Kimble, PharmD, dean of the School of Pharmacy at University of California, San Francisco, was awarded the 2010 Remington Honor Medal, the highest honor given by the American Pharmacists Association, at its recent annual meeting in Washington. 2010-05-05T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/192010/668534null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Compounded-drugs-give-indies-an-edge/ArticleStandard/Article/detail/668532?contextCategoryId=47453&ref=25 Compounded medicines &amp;mdash; also called personalized solutions &amp;mdash; have become an important element in many independent pharmacies. 2010-05-05T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/192010/668532/drtp_0510_barnett_RFC_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Avandia-safety-under-fire-again/ArticleStandard/Article/detail/668533?contextCategoryId=47453&ref=25 A report issued by the Senate Finance Committee earlier this year noted that Avandia is associated with 83,000 excess heart attacks occurring between 1999 and 2007. 2010-05-05T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/192010/668533null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/FDA-approves-brand-name-change-for-dexlansoprazole/ArticleStandard/Article/detail/668537?contextCategoryId=47453&ref=25 FDA would like to alert healthcare providers to the recent proprietary name change for dexlansoprazole delayed-release capsules. Now known as Dexilant, dexlansoprazole is the proton pump inhibitor formerly known as Kapidex. 2010-05-05T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/192010/668537/drtp0510_dexilant_RFC_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/New-black-box-warning-for-clopidogrel/ArticleStandard/Article/detail/668524?contextCategoryId=47453&ref=25 FDA announced that clopidogrel, an antiplatelet agent given to reduce the risk of heart attack, unstable angina, stroke, and cardiovascular death in patients with cardiovascular disease, will require a new black-box warning about its reduced effectiveness in patients who are poor metabolizers of the drug. 2010-05-05T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/192010/668524null XML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/OxyContins-new-formulation-approved-by-FDA/ArticleStandard/Article/detail/666238?contextCategoryId=47453&ref=25 A reformulation of controlled-release oxycodone (OxyContin, Purdue Pharma), designed to curb misuse and abuse of the drug, has received FDA approval. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666238null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Global-TB-collaboration-pushes-to-generate-more-ef/ArticleStandard/Article/detail/666233?contextCategoryId=47453&ref=25 FDA Commissioner Margaret Hamburg, MD, addressed health leaders worldwide who represent industry, academia, government, and advocacy to help kick off a global consortium to fight tuberculosis (TB). She recently spoke at a press conference in Washington. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666233null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Inhalers-filled-with-ozone-depleting-ingredients-w/ArticleStandard/Article/detail/666245?contextCategoryId=47453&ref=25 Seven metered-dose inhalers for treatment of asthma and chronic obstructive pulmonary disease will soon be phased out, according to FDA. The move goes along with U.S. commitments to the Montreal Protocol on Substances that Deplete the Ozone Layer. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666245null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Rosuvastatins-expanded-indication-draws-criticism/ArticleStandard/Article/detail/666237?contextCategoryId=47453&ref=25 Following FDA?s expanded indication for rosuvastatin (Crestor, AstraZeneca) in February, the drug?s producer now plans to extend the market for the drug by offering it as a preventive measure to people who do not have cholesterol issues. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666237null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Galderma-gains-FDA-approval-for-retinoid-in-lotion/ArticleStandard/Article/detail/666235?contextCategoryId=47453&ref=25 Galderma Laboratories has received FDA approval for adapalene lotion, 0.1% (Differin), a first-of-its-kind lotion formulation of the retinoid adapalene for treating acne. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666235null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Liraglutide-may-improve-glycemic-control-in-patien/ArticleStandard/Article/detail/666236?contextCategoryId=47453&ref=25 Patients taking oral antidiabetes drugs who switched from exenatide twice daily to liraglutide once daily experienced further reductions in hemoglobin A1c and weight loss, according to the results of a clinical study. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666236null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Drug-approved-as-adjunctive-therapy-for-treatment-/ArticleStandard/Article/detail/666234?contextCategoryId=47453&ref=25 Carglumic acid tablets (Carbaglu, Orphan Europe) for treatment of a rare genetic condition characterized by excess ammonia in the blood have received FDA approval. 2010-04-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/172010/666234null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Pharmacist-intervention-boosts-patient-compliance/ArticleStandard/Article/detail/664504?contextCategoryId=47453&ref=25 While approximately 40% of patients with schizophrenia have been partly or entirely nonadherent with antipsychotic medications, patient adherence improved dramatically when Veterans Affairs pharmacy staff coordinated these patients' medications, according to a new study. 2010-04-07T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/152010/664504/blisterpack_pg27_april_2010_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/CME+Showcase/New-drugs-update-2009-approvals-part-2-CE/CME/Article/detail/664557?contextCategoryId=47453&ref=25 This continuing education article provides a review of new molecular entities and biologics approved by the FDA in 2009 that were not mentioned in part 1 of this series. 2010-04-07T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/cme/drugtopics/152010/664557null REMOTE http://drugtopics.modernmedicine.com/drugtopics/Pharmacy/Opioid-REMS-may-require-pharmacist-certification/ArticleStandard/Article/detail/661463?contextCategoryId=47453&ref=25 REMS for opioids may present some tough challenges for pharmacists. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661463null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Pediatric-rehydration-formulary-under-review/ArticleStandard/Article/detail/661451?contextCategoryId=47453&ref=25 Pharmacy and Therapeutics committees around the country are taking a second look at what they're using for pediatric rehydration and how much they're willing to pay. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661451/Mar_2010_sick_kid_1_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Rep-Marion-Berry-garners-NACDS-leadership-award/ArticleStandard/Article/detail/661469?contextCategoryId=47453&ref=25 The National Association of Chain Drug Stores (NACDS) awarded Rep. Marion Berry the NACDS Congressional Leadership Award for his ongoing support of pharmacy. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661469null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Medication-therapy-management-at-a-community-pharm/ArticleStandard/Article/detail/661452?contextCategoryId=47453&ref=25 Medication therapy management programs are intended to improve patient outcomes and reduce healthcare costs. Community pharmacist Tony Bastian offers a detailed report on how MTM is working at his pharmacy. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661452/Mar_2010_pharm-patient_pg18_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Investigational-drug-may-boost-survival-for-certai/ArticleStandard/Article/detail/661431?contextCategoryId=47453&ref=25 Cabazitaxel, an investigational compound under development by Sanofi-aventis, plus prednisone/prednisolone, is associated with overall survival and progression-free survival in patients with metastatic (advanced) hormone-refractory prostate cancer whose disease advanced after treatment with docetaxel-based chemotherapy. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661431null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Injection-pen-will-aid-those-with-growth-hormone-r/ArticleStandard/Article/detail/661441?contextCategoryId=47453&ref=25 Norditropin FlexPro (somatropin [rDNA origin] injection, Novo Nordisk), a pre-filled injection pen for use in children and adults with growth hormone disorders, will be available this spring. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661441null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/IOM-calls-for-research-on-vaccination-delivery-sit/ArticleStandard/Article/detail/661453?contextCategoryId=47453&ref=25 The Institute of Medicine says more research is necessary comparing the advantages of different sites for vaccination. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661453null XML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Transdermal-patch-in-development-stages-may-prove-/ArticleStandard/Article/detail/661422?contextCategoryId=47453&ref=25 Data from the Phase III trial of Zelrix, a transdermal patch under development by NuPathe Inc. for management of acute migraine, showed the patch met the primary efficacy endpoint. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661422null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/The-pros-and-cons-of-mail-order-pharmacy/ArticleStandard/Article/detail/661462?contextCategoryId=47453&ref=25 Whether mail-order pharmacy is a blessing or a bane depends on whom you ask. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661462/Mar_2010_192x210_cover_flash.jpg XML http://drugtopics.modernmedicine.com/drugtopics/Clinical+News/New-drugs-update-2009-approvals-part-1-CE/CME/Article/detail/661760?contextCategoryId=47453&ref=25 This article provides a review of new molecular entities and biologics approved by the FDA in 2009. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/cme/drugtopics/122010/661760null REMOTE http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/First-direct-thrombin-inhibitor-cleared-for-DVT-pr/ArticleStandard/Article/detail/661421?contextCategoryId=47453&ref=25 The FDA-approved Iprivask (desirudin for injection, Canyon Pharmaceuticals), now available, marks the first direct thrombin inhibitor (DTI) OK'd for the prevention of deep vein thrombosis (DVT). 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661421null HTML http://drugtopics.modernmedicine.com/drugtopics/Pharmacy+News/Opioid-analgesic-on-market-for-cancer-pain-managem/ArticleStandard/Article/detail/661437?contextCategoryId=47453&ref=25 An FDA-approved oral transmucosal fentanyl citrate, an opioid analgesic for cancer pain management, is being launched by Mallinckrodt Inc., a Covidien company. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661437null HTML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/Medications-donated-to-Kansas-clinics/ArticleStandard/Article/detail/661458?contextCategoryId=47453&ref=25 More than $600,000 of unused medications were donated to Kansas clinics last year. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661458null XML http://drugtopics.modernmedicine.com/drugtopics/Modern+Medicine+Now/FDA-curbs-LABA-use-for-asthma/ArticleStandard/Article/detail/661467?contextCategoryId=47453&ref=25 FDA recommended drastic changes limiting the way long-acting beta2-adrenergic agonists are used to treat asthma. 2010-03-15T04:00:00Z http://drugtopics.modernmedicine.com/drugtopics/data/articlestandard/drugtopics/122010/661467null XML