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    Small Doses: The Weekly News You Need to Know

    News from the week of March 6 delivered to you.


    Hitting the target

    Two Approaches Allow Safe Increase in Use of Penicillin and Cephalosporins

    More hospitalized patients can be treated safely with penicillin and cephalosporins if a skin test and a computerized decision support tool are used. Many patients may have an allergy to penicillin or other antibiotics in their medical records but are not actually allergic. Finding out which patients can safely be given these highly-effective antibiotics can increase their use and cut down on the use of less-effective drugs. A study published in the Journal of Allergy and Clinical Immunology evaluated both the skin test and a computerized treatment guideline that is based on the type of symptoms a patient said they experienced with past penicillin use. Both strategies safely increased the use of penicillin or cephalosporins in these patients.

    Blumenthal KG et al: Tackling inpatient penicillin allergies: Tools for antimicrobial stewardship. J Allergy Clin Immunol. 2017 Feb 27. pii: S0091-6749(17)30325-1. doi: 10.1016/j.jaci.2017.02.005.

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    Valerie DeBenedette
    Valerie DeBenedette is Managing Editor of Drug Topics.


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