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Pfizer launches dual-chamber syringe for patients with hemophilia


Pfizer Inc. recently launched a syringe that aims to help hemophilia patients lead active lives and take care of their condition faster and easier.

Its new Prefilled Dual-Chamber Syringe to administer Xyntha antihemophilic factor (recombinant) plasma/albumin-free includes the Xyntha powder and the diluents within the syringe. This eliminates the transfer step during reconstitution.

“All you have to do is push one button. In the past, [antihemophilic syringes] were multi-step kits with a syringe, several needles, and 2 vials,” said Marcus Carr, Jr., MD, PhD, FACP, Hematology Disease Area Lead for Pfizer’s Specialty Care Business Unit. The Dual-Chamber Syringe is easier for patients — who typically don’t have full range of motion in one or both arms — and for their caregivers to use, Carr said.

The syringe is used to deliver Xyntha by intravenous infusion after reconstitution of a freeze-dried powder with the diluents (0.9% sodium chloride). The new, prefilled syringe provides 3,000 IU of plasma, the highest dose, in a low, 4 mL volume. Other dosages of Xyntha will be available in the Dual-Chamber Syringe later this year.

Xyntha is a recombinant factor VIII product indicated for both the control and prevention of bleeding episodes in patients with hemophilia A and for surgical prophylaxis in patients with hemophilia A.

The United States Department of Health and Human Services division of Substance Abuse and Mental Health Services Administration has released a study examining trends of admissions to U.S. substance abuse treatment facilities of people aged 12 years and over, during the period from 1998 to 2008.

In this section we showcase products and product news that ran up against space limitations or fell outside the parameters of recently featured categories in the print edition. Look for more OTC Product News in upcoming issues of the Drug Topics e-newsletter.

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